Large volume-complex matrix injection-gas chromatography-mass spectrometry for detection of pesticide residues in lettuce and peas

Since ethyl acetate generally has a higher recovery rate for pesticides of different polarities, it is often used as an organic solvent for pesticide residue detection in food. Before the extracted sample is analyzed by gas chromatography, it is usually necessary to undergo some purification treatment to remove the interfering matrix in the sample (such as solid phase extraction and gel permeation chromatography), otherwise the inlet of the gas chromatography and the chromatography column are vulnerable to contamination , Which in turn reduces chromatographic performance. However, these purification steps will not only increase the sample preparation time but also increase the amount of solvent used and increase the analysis cost.

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