The micro-neural circuit of the brain makes it easier for young people to learn, and the mechanism for older people to learn more difficult. The researchers revealed an element of the brain circuit during the critical period of learning: the behavior of inhibitory neurons.
About 80% of neurons are excitatory neurons. Using traditional scientific tools, scientists can only study excitatory neurons.
The popular doctrine of inhibitory neurons believes that as inhibitory neurons mature, their activity levels increase, leading to the best learning period. But as the brain enters adulthood, inhibitory neurons continue to mature, and their activity is further enhanced to hinder learning.
"We have learned from past studies that excitatory nerve cells are responsible for transmitting information. We also know that inhibitory neurons play a crucial role in establishing a high degree of plasticity, but for how these cells actually achieve this function There is controversy. Since we cannot study these cells, we can only speculate on their behavior during the critical learning period, "
The brain is made up of two types of cells: inhibitory neurons and excitatory neurons. The neural network composed of these two neurons is responsible for processing sensory information such as images, sounds and smells, and performing cognitive functions.
Using the newly developed genetic and imaging technology, the researchers developed inhibitory neurons in the brain and recorded their activity in response to various stimuli. As a postdoctoral student in the laboratory of Joshua T. Trachtenberg, associate professor of neurobiology at the University of California, Los Angeles, Kuhlman and colleagues used these new technologies to record the activity of inhibitory neurons during key learning periods. They found that inhibitory nerves did not fire more frequently than expected during intensive learning, on the contrary, their discharge frequency decreased to only half of the usual.
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